Spectrum of Biopsy Proven Multisystemic Sarcoidosis in Pakistan: A Systemic Review

Abstract

Sarcoidosis is a granulomatous disorder affecting multiple organs and systems however, its etiology is unknown. It is characterized by formation of non-caseating granulomas in the affected organs. The most common sites involved include lungs and the lymphoid system. Extrapulmonary involvement has also been reported with abdomen being the most common extrapulmonary site. Other systems involved include the skin, the eyes; the liver and spleen; the heart; the nervous system, musculoskeletal system, renal, and endocrine systems. This review article will help explore the different manifestations of sarcoidosis in various organs.