Liver Fibrosis-Novel Therapy Perspective

Abstract

Liver fibrosis is highly prevalent in United States. No therapy has been successful to cure it so far. The current approaches in treatment are to prevent its causative etiology such as viral infection, alcohol abuse etc. or liver transplantation. Much progress has been made to understand the mechanisms for development of myofibroblasts in developing fibro genesis, inflammation and cell death. This review summarizes some of the key aspects of liver fibrosis and some novel therapies that have a potential to become a cure.