Preparation and Characterization of Sodium Alginate- Eudragit E100 Based Systems with Prospective Pharmaceutical Delivery to Application

Authors

  • Voycheva CH* Faculty of Pharmacy, Medical University of Sofia, Bulgaria Author

DOI:

https://doi.org/10.23880/oajpr-16000254

Keywords:

Sodium Alginate, Eudragit E 100, Interpolymer Complexes, Modified Release, Biocompatibility

Abstract

Regarding the preparation of a local drug delivery system, the possibility of incorporating an active substance in a matrix system was investigated to prolong the drug release. A complex between sodium alginate and a triple copolymer of dimethyl aminoethyl methacrylate was prepared in the presence of a cross-linking agent- malic acid. The formation of a polyelectrolyte complex was proven by turbidimetry, determining the specific viscosity of the diluted solutions of sodium alginate, EE 100, malic acid with IR spectroscopy.

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Published

2021-11-23

Issue

Vol. 5 No. 4 (2021)

Section

Articles

License

Copyright (c) 2021 Voycheva CH

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Preparation and Characterization of Sodium Alginate- Eudragit E100 Based Systems with Prospective Pharmaceutical Delivery to Application. (2021). Open Access Journal of Pharmaceutical Research, 5(4), 1-4. https://doi.org/10.23880/oajpr-16000254

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