Chemical Composition and Biological Activity of Essential Oil from Cotula cinerea (Del.) Growing Wildly in the Middle East: A Short Review

Authors

  • El-Fiky FK Department of Pharmacognosy, Delta University for Science and Technology, Egypt Author
  • Dekinash MF Department of Pharmacognosy, Damanhour University, Egypt Author
  • Beltagy AM Department of Pharmacognosy, Damanhour University, Egypt Author
  • El-naggar MA Department of Pharmacognosy, Damanhour University, Egypt Author
  • Khattab AR 3Department of Pharmacognosy, Division of Pharmaceutical Sciences, College of Pharmacy, Arab Academy for Science, Technology and Maritime Transport, Egypt Author

DOI:

https://doi.org/10.23880/ipcm-16000103

Keywords:

Cotula cinerea, Essential oil, Biological activity, GC/MS analysis

Abstract

The essential oil extracted from Egyptian xerophytic plant named “Cotulacinerea” is used in broncho-pulmonary diseases
due to the expectorant and antiseptic effects of its oil a topical application to relieve pain and to promote healing and also
finds use in the fragrance and flavouring industries. The main constituents of the essential oil are Camphor, Camphene,
Alpha-pinene, 3-carene, Thujone, 4-terpineol, (Z)-betafarnesene and santolinatriene. The biological activity of C.cinerea
essential oil has been investigated. The oil possessed significant antibacterial, antifungal, anticandidal activities. However,
the oil showed low antioxidant capacity. Concerning its anti tumour activity, there was a scarce work on examining the oil
antitumor activity. Only one study showed that the oil has moderate cytotoxic activity against both colorectal
adenocarcinoma and hepatocellular carcinoma cell lines.

Published

2017-03-13

Issue

Vol. 1 No. 1 (2017)

Section

Articles

License

Copyright (c) 2017 El-Fiky FK

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.