Sub-Nephrotic Proteinuria as the Indication for a Kidney Biopsy: Review

Abstract

Sub-nephrotic proteinuria as a clinical syndrome and an indication to renal biopsy has not much attention. In this systematic review, series from 24 studies have been researched. IgA nephropathy, MesPGN and MGN were respectively defined as the most likely diagnoses for patients undergoing renal biopsies due to sub-nephrotic proteinuria. Profound disparities were also detected with regard to the patients’ region of origin as well as their age subgroup. Due to the limitation of the number of series reporting data on sub-nephrotic proteinuria and associated pathological diagnoses, further data coming with the prospective reports are necessary to make more precise estimations.